Knox County Tennessee

Substance Misuse Response Division

The Knox County Health Department collaborates with community partners to prevent overdose deaths, increase awareness about factors that lead to preventable deaths, and strengthen community responsiveness to substance misuse.

We strive for an overdose-free county where people feel no stigma when seeking out treatment services and have the support system they need to achieve their recovery goals. Substance use disorder is curable, and both substance misuse and overdose deaths are preventable.

KCHD’s Substance Misuse Response Division houses:

  • All4Knox, a joint substance misuse response initiative of Knox County and the City of Knoxville
  • Public health education on substance misuse and related topics
  • Naloxone and fentanyl test strip distribution
  • Community HIV and Hepatitis C testing
  • Peer navigation for substance use and mental health disorders

Our division also works closely with the KCHD’s epidemiology department to monitor drug-related trends and communicate findings to community partners as needed. Explore this page to see our resources for you, a loved one or your business/organization.


Substance Misuse Response Division Contact: 865-215-5355.

Health Department logo

Have Questions?
Call: 865-215-5555

Need to report a public
health emergency?

Call 865-215-5093

On the first Wednesday of every month, all KCHD offices and clinics are closed in the morning for staff in-service. On these days, the main location (140 Dameron Ave.) will open at 11 a.m. and the West Clinic (1028 Old Cedar Bluff) will open at 11:30 a.m.

Clinics will also open at 10:30 a.m. (Main location) and 11 a.m. (West Clinic) on the following Wednesdays: April 17 and July 17. All other offices will open at 8 a.m.